POMEGRANATE - Uses, Side Effects, and More

Abidov, M., Jimenez Del, Rio M., Ramazanov, A., Kalyuzhin, O., and Chkhikvishvili, I. Efficiency of pharmacologically-active antioxidant phytomedicine Radical Fruits in treatment hypercholesteremia at men. Georgian.Med News 2006;(140):78-83. View abstract.

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Abidov, M., Ramazanov, Z., Seifulla, R., and Grachev, S. The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat. Diabetes Obes.Metab 2010;12(1):72-81. View abstract.

Adams, L. S., Seeram, N. P., Aggarwal, B. B., Takada, Y., Sand, D., and Heber, D. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. J Agric Food Chem 2-8-2006;54(3):980-985. View abstract.

Adams, L. S., Zhang, Y., Seeram, N. P., Heber, D., and Chen, S. Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro. Cancer Prev.Res.(Phila) 2010;3(1):108-113. View abstract.

Adhikari, A., Devkota, H. P., Takano, A., Masuda, K., Nakane, T., Basnet, P., and Skalko-Basnet, N. Screening of Nepalese crude drugs traditionally used to treat hyperpigmentation: in vitro tyrosinase inhibition. Int.J Cosmet.Sci 2008;30(5):353-360. View abstract.

Adiga, S. Trivedi P. Ravichandra V. Deb D. and Mehta F. Effect of Punica granatum peel extract on learning and memory in rats. Asian Pacific Journal of Tropical Medicine 2010;3(9):687-690.

Afaq, F., Khan, N., Syed, D. N., and Mukhtar, H. Oral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis. Photochem.Photobiol. 2010;86(6):1318-1326. View abstract.

Afaq, F., Malik, A., Syed, D., Maes, D., Matsui, M. S., and Mukhtar, H. Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign. Photochem Photobiol 2005;81(1):38-45. View abstract.

Afaq, F., Saleem, M., Krueger, C. G., Reed, J. D., and Mukhtar, H. Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice. Int J Cancer 1-20-2005;113(3):423-433. View abstract.

Afaq, F., Zaid, M. A., Khan, N., Dreher, M., and Mukhtar, H. Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin. Exp.Dermatol. 2009;18(6):553-561. View abstract.

Ahshawat, M. S., Saraf, S., and Saraf, S. Preparation and characterization of herbal creams for improvement of skin viscoelastic properties. Int.J Cosmet.Sci. 2008;30(3):183-193. View abstract.

Al-Mustafa, A. H. and Al-Thunibat, O. Y. Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes. Pak.J.Biol.Sci. 2-1-2008;11(3):351-358. View abstract.

Al-Zoreky, N. S. Antimicrobial activity of pomegranate (Punica granatum L.) fruit peels. Int.J.Food Microbiol. 9-15-2009;134(3):244-248. View abstract.

Alam, M. S., Alam, M. A., Ahmad, S., Najmi, A. K., Asif, M., and Jahangir, T. Protective effects of Punica granatum in experimentally-induced gastric ulcers. Toxicol.Mech.Methods 2010;20(9):572-578. View abstract.

Albrecht, M., Schneider, O., and Schmidt, A. Redox active donor-substituted punicin derivatives. Org.Biomol.Chem. 4-7-2009;7(7):1445-1453. View abstract.

Alighourchi, H. Barzegar M. and Abbasi S. Effect of gamma irradiation on the stability of anthocyanins and shelf-life of various pomegranate juices. Food Chemistry 2008;110(4):1036-1040.

Aviram, M., Dornfeld, L., Kaplan, M., Coleman, R., Gaitini, D., Nitecki, S., Hofman, A., Rosenblat, M., Volkova, N., Presser, D., Attias, J., Hayek, T., and Fuhrman, B. Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans. Drugs Exp.Clin.Res. 2002;28(2-3):49-62. View abstract.

Aviram, M., Dornfeld, L., Rosenblat, M., Volkova, N., Kaplan, M., Coleman, R., Hayek, T., Presser, D., and Fuhrman, B. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am.J.Clin.Nutr. 2000;71(5):1062-1076. View abstract.

Bachoual, R., Talmoudi, W., Boussetta, T., Braut, F., and El-Benna, J. An aqueous pomegranate peel extract inhibits neutrophil myeloperoxidase in vitro and attenuates lung inflammation in mice. Food Chem.Toxicol. 2011;49(6):1224-1233. View abstract.

Bae, J. Y., Choi, J. S., Kang, S. W., Lee, Y. J., Park, J., and Kang, Y. H. Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation. Exp.Dermatol. 2010;19(8):e182-e190. View abstract.

Bagri, P., Ali, M., Aeri, V., Bhowmik, M., and Sultana, S. Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Food Chem.Toxicol. 2009;47(1):50-54. View abstract.

Bagri, P., Ali, M., Sultana, S., and Aeri, V. New sterol esters from the flowers of Punica granatum Linn. J.Asian Nat.Prod.Res. 2009;11(8):710-715. View abstract.

Balwani, S., Nandi, D., Jaisankar, P., and Ghosh, B. 2-Methyl-pyran-4-one-3-O-beta-D-glucopyranoside isolated from leaves of Punica granatum inhibits the TNFalpha-induced cell adhesion molecules expression by blocking nuclear transcription factor-kappaB (NF-kappaB). Biochimie 2011;93(5):921-930. View abstract.

Belal, S. K. M. Abdel-Rahman A. H. Mohamed D. S. Osman H. E. H. and Hassan N. A. Protective effect of pomegranate fruit juice against Aeromonas hydrophila-induced intestinal histopathological changes in mice. World Applied Sciences Journal 2009;7(2):245-254.

Bell, C. and Hawthorne, S. Ellagic acid, pomegranate and prostate cancer -- a mini review. J.Pharm.Pharmacol. 2008;60(2):139-144. View abstract.

Beltz, J. McNeil C. Fisher M. Shaw P. Breece L. Sellers T. andBrown K. Investigation of the antihyperalgesic effects of the pomegranate extract ellagic acid. AANA Journal 2008;76(5):365-366.

Ben-Simhon, Z., Judeinstein, S., Nadler-Hassar, T., Trainin, T., Bar-Ya'akov, I., Borochov-Neori, H., and Holland, D. A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development. Planta 2011;234(5):865-881. View abstract.

Benherlal, P. S. and Arumughan, C. Studies on modulation of DNA integrity in Fenton's system by phytochemicals. Mutat.Res. 12-15-2008;648(1-2):1-8. View abstract.

Benzer, F. Kandemir F. M. Yildirim N. C. and Ozan S. T. Effect of pomegranate seed extract on free radical damage and antioxidant activity under cisplatin-induced oxidative stress conditions in rabbit testes. Asian Journal of Chemistry 2011;23(7):3131-3234.

Bhadbhade, S. J., Acharya, A. B., Rodrigues, S. V., and Thakur, S. L. The antiplaque efficacy of pomegranate mouthrinse. Quintessence.Int. 2011;42(1):29-36. View abstract.

Bialonska, D., Kasimsetty, S. G., Khan, S. I., and Ferreira, D. Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay. J.Agric.Food Chem. 11-11-2009;57(21):10181-10186. View abstract.

Bialonska, D., Kasimsetty, S. G., Schrader, K. K., and Ferreira, D. The effect of pomegranate (Punica granatum L.) byproducts and ellagitannins on the growth of human gut bacteria. J.Agric.Food Chem. 9-23-2009;57(18):8344-8349. View abstract.

Bishayee, A., Bhatia, D., Thoppil, R. J., Darvesh, A. S., Nevo, E., and Lansky, E. P. Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms. Carcinogenesis 2011;32(6):888-896. View abstract.

Borochov-Neori, H., Judeinstein, S., Harari, M., Bar-Ya'akov, I., Patil, B. S., Lurie, S., and Holland, D. Climate effects on anthocyanin accumulation and composition in the pomegranate (Punica granatum L.) fruit arils. J.Agric.Food Chem. 5-25-2011;59(10):5325-5334. View abstract.

Bouroshaki, M. T., Sadeghnia, H. R., Banihasan, M., and Yavari, S. Protective effect of pomegranate seed oil on hexachlorobutadiene-induced nephrotoxicity in rat kidneys. Ren Fail. 2010;32(5):612-617. View abstract.

Boussetta, T., Raad, H., Letteron, P., Gougerot-Pocidalo, M. A., Marie, J. C., Driss, F., and El-Benna, J. Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats. PLoS.One. 2009;4(7):e6458. View abstract.

Calin-Sanchez, A., Martinez, J. J., Vazquez-Araujo, L., Burlo, F., Melgarejo, P., and Carbonell-Barrachina, A. A. Volatile composition and sensory quality of Spanish pomegranates (Punica granatum L.). J.Sci.Food Agric. 2011;91(3):586-592. View abstract.

Carpenter, L. A. Conway C. J. and Pipkin F. B. Pomegranates (Punica granatum) and their effect on blood pressure: a randomised double-blind placebo-controlled trial. Proceedings of the Nutrition Society 2010;69(1):95.

Cayir, K., Karadeniz, A., Simsek, N., Yildirim, S., Karakus, E., Kara, A., Akkoyun, H. T., and Sengul, E. Pomegranate seed extract attenuates chemotherapy-induced acute nephrotoxicity and hepatotoxicity in rats. J.Med.Food 2011;14(10):1254-1262. View abstract.

Celik, I., Temur, A., and Isik, I. Hepatoprotective role and antioxidant capacity of pomegranate (Punica granatum) flowers infusion against trichloroacetic acid-exposed in rats. Food Chem.Toxicol. 2009;47(1):145-149. View abstract.

Cerda, B., Espin, J. C., Parra, S., Martinez, P., and Tomas-Barberan, F. A. The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans. Eur.J.Nutr. 2004;43(4):205-220. View abstract.

Choi, J. G., Kang, O. H., Lee, Y. S., Chae, H. S., Oh, Y. C., Brice, O. O., Kim, M. S., Sohn, D. H., Kim, H. S., Park, H., Shin, D. W., Rho, J. R., and Kwon, D. Y. In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. Evid.Based.Complement Alternat.Med. 2011;2011:690518. View abstract.

Choi, S. J., Lee, J. H., Heo, H. J., Cho, H. Y., Kim, H. K., Kim, C. J., Kim, M. O., Suh, S. H., and Shin, D. H. Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice. J.Med.Food 2011;14(7-8):695-701. View abstract.

Chong, M. F., Macdonald, R., and Lovegrove, J. A. Fruit polyphenols and CVD risk: a review of human intervention studies. Br.J.Nutr. 2010;104 Suppl 3:S28-S39. View abstract.

Cuccioloni, M., Mozzicafreddo, M., Sparapani, L., Spina, M., Eleuteri, A. M., Fioretti, E., and Angeletti, M. Pomegranate fruit components modulate human thrombin. Fitoterapia 2009;80(5):301-305. View abstract.

Dahham, S. S. Ali M. N. Tabassum H. and Khan M. Studies on antibacterial and antifungal activity of pomegranate (Punica granatum L.). American-Eurasian Journal of Agricultural and Environmental Science 2010;9(3):273-281.

Dai, Z., Nair, V., Khan, M., and Ciolino, H. P. Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro. Oncol.Rep. 2010;24(4):1087-1091. View abstract.

Darji, V. C. Bariya A. H. Deshpande S. S. and Patel D. A. Effect of Punica granatum fruits in inflammatory bowel disease. Journal of Pharmacy Research 2010;3(12):2850-2852.

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